I am trying to do bioinformatics analysis for LGG and GBM cohort from TCGA. I encountered a difficulty because I am not sure if I counted correctly whether the LGG cohort is heterogeneous or homogeneous in terms of IDH1 status (WT or Mutant). Can somebody help me do that or did it already? :) Thank You in advance for Your help :)
It is heterogenous for idh status. Moreover you can also check chinese glioma genome atlas.
Thank You for Your response. But do You calculate that somehow? Or think that way because it is not homogenous in 100%? :)
Thank You for recommendation of CGG Atlas :) I found there useful information about subtypes :)
In what context you are referring IDH homogeneity to?
In case you are asking about homozygous or heterozygous mutation, then it is mostly heterozygous missense mutation. homozygous IDH mutations in lower grade gliomas are rare.
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