02 February 2017 2 2K Report

Good Evening,

I have to use the Lawesson's reagent on a compound that contains a ketone and a free amine and I wanted to know if it was necessary to protect the amine ( with Boc for example) before the Lawesson reaction ? In other terms, can the  Lawesson's reagent react with the amine ?

Thank you by advance 

respecfully yours 

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