Kinship assessment with SNP data?

More Santiago Montero-Mendieta's questions See All

What can a shift in Zn2p edge of ZnO/CuO nanocomposites mean in XPS?

I synthesized pure ZnO with a hydrothermal microwave method and decorated them with CuO with the incipient wetness impregnation method. The Zn2p edges of pure ZnO are at 1044.7 and 1021.6 eV...

18 June 2024 9,405 2 View

In South Africa, how do environmentally conscious consumers perceive the product innovation strategies of plastic converters?

Has anyone perhaps got any information on how environmentally conscious consumers perceive the product innovation strategies of plastic manufacturers?

19 April 2024 1,734 3 View

What are the impacts of regional variations in antibiotic resistance patterns on patient outcomes, and what can be done to address these variations?

This question was asked to understand how variations in antibiotic resistance across different regions affect the way patients are treated and how their health outcomes are affected. The inquiry...

22 February 2024 3,339 2 View

Besides Rietveld refinement is there another methodology to do a quantitative analysis with XRD data?

i just want to know if there are more options to do a quantitative analysis with xrd data

02 February 2024 2,458 2 View

How can I carry out the "shortest path analysis" using an undirected graph with negative weight edges?

I'm currently working on a project that involves conducting a "shortest path analysis" using an undirected graph with negative weight edges (Mixed graphical model, MGM). I know that traditional...

25 January 2024 8,589 2 View

Economics ,prices and privatisation as a solution for water sector management?

Economic market implementation for water and involvement of private sector in water management

11 January 2024 6,972 1 View

Any interesting work about pulmonary vascular resistance and pulmonary total resistance among high-altitude dwellers?

I am interested in different techniques assessment through the years (i.e., 50´s and nowadays) and clear definitions of both terms, as well. Thanks in advance!

15 November 2023 2,398 1 View

Conversion of Odd Ratio of log-transformed variable to OR of original variable in logistic regression?

I have retrieved a study that reports a logistic regression, the OR for the dichotomous outcome is 1.4 for the continuous variable ln(troponin) . This means that the Odds increase 0.4 every...

14 November 2023 8,513 3 View

Convert odds ratio of a regression with a continuous variable, to OR of a dichotomous variable?

I have the OR of a logistic regresion that used the independent variable as continuous. I also have the ORs of 2x2 tables that dichotomized the variable (high if >0.1, low if < 0.1). Is...

13 November 2023 8,230 4 View

Is there any defined and scientifically accepted range of relative frequency of myeloid suppressor cells (MDSC) in healthy people?

Good afternoon. I'm trying to research about MDSC in humans. Certainly there's a lot of research about frequency of MDSC (measured by flow cytometry) positively correlated with the progression...

11 August 2023 4,922 1 View

I can't see the ssDNA band after performing asymmetric PCR. Is there any way to do this?

After performing symmetric PCR, PCR purification was performed. Afterwards, asymmetric PCR was performed using the PCR purification product as a template, but no ssDNA band was confirmed in the...

08 August 2024 1,668 3 View

Why Powder XRD is performed after cruhsing a crystal if Single Crystal XRD analysis of the same crystal has been performed already ?

What information we can get from PXRD analysis other than from SCXRD analysis of a crystal ?

30 July 2024 6,261 4 View

Inquiry on Maximum Nucleic Acid Volume for 2.5 mL Liposome Solution?

I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...

30 July 2024 6,420 1 View

How to know the b axis of a single crystal?

How to apply magnetic field parallel to b axis of any crystal

29 July 2024 4,083 2 View

Can anyone help me explain my problem?

Hi, Now I am doing a single-base editing by using HiFi Cas 9, guideRNA, single stranded DNA, HDR Enhancer V2 and my tranfection mehtod is lipofection (RNAiMax). Unfortunately, after gene editing,...

26 July 2024 2,136 0 View

Are there any alternatives to PhenoScanner?

I am currently conducting a mendelian randomization study, and I was attempting to use PhenoScanner to look for potential confounders associated with the selected SNPs (any SNPs significantly...

23 July 2024 5,703 0 View

What are the strategies to Enhance IgG-Producing Plasma Cells in mice for Monoclonal Antibody Development?

I have immunized BalB/C mice with a protein using the intradermal (ID) method with Complete Freund's Adjuvant (CFA) and Incomplete Freund's Adjuvant (IFA), following a 14-day interval and three...

22 July 2024 9,160 2 View

Can someone please explain to me what power law statistics mean in single molecule fluorescence blinking ?

I am a beginner in this field. While I am reading papers and the understanding is getting better. However can someone explain in easy and simple words. Really thankful !

08 July 2024 8,337 5 View

Is it possible to generate a (semi-)permanent "transcription bubble" within a replicable plasmid?

I was wondering if it is possible to form a permanent open "ssDNA bubble" similar to a transcription bubble (>13 nucleotides) within E. coli. These criteria are important: 1. Open ssDNA...

07 July 2024 8,275 5 View

How would I calculated ddPCR spiked nucleic acid recovery calculations?

Hello everyone, I'm in the initial stages of conducting a study involving the ddPCR (Bio-Rad QX200, QX600) and I ran into some problems involving recovery % calculations using direct...

02 July 2024 6,011 2 View

Jacqueline Lane

We typically use PLINK for this. https://www.cog-genomics.org/plink/1.9/ibd In this case we use the metric pihat, and consider pihat >= .125 as related indivs (so related as cousins or closer). It's a good idea to look at the distribution of pihat in your data and see what the population mean is.

Santiago Montero-Mendieta

Thanks a lot Maxim Freidin

and Jacqueline Lane !