In the past there has been research indicating REM sleep activity may be inversely related to epileptic activity. I am interested in an updated exploration of the relationship between REM sleep, schizophrenic hallucinations and epileptic activity, in terms of neuroanatomy and neurophysiology (including related neuromodulators).
We have published a few years ago a paper on Clinical Neurophysiology ( Clin Neurophysiol 2005; 116: 1520-1532) where we have analyzed the relationship between sleep state and ictal seizures in neonates. We have observed a predominance of seizures in REM sleep in this population and we have hypothesized that in the developing brain the expression of ictal activity may have an age dependent mechanism.
These articles may lead to a conclusion.:
http://www.jneurosci.org/content/34/2/566.abstract-
Dopaminergic role in regulating markers of sleep homeostasis
The Journal of Neuroscience, 8 January 2014, 34(2): 566-573; doi: 10.1523/JNEUROSCI.4128-13.2014
Influence of Sleep and Sleep Deprivation on Ictal and ..
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The role of sleep dysfunction in the occurrence of delusions ...
www.sciencedirect.com/science/article/.../S027273581500119...
ScienceDirect
by S Reeve - 2015 - Cited by 3 - Related articles
Sleep dysfunction is extremely common in patients with schizophrenia. ... and psychotic experiences, particularly delusions and hallucinations. ...... the variation (63%) in high frequency EEG activity during REM sleep (Tekell et al., 2005).
www.hindawi.com/journals/ert/2013/492524
... (Non Rapid Eye Movement) sleep, ... Epileptiform Activity. The effects of sleep ... a variation during sleep with typical EEG with ...
Published in:
Epilepsy Research and Treatment · 2013
Authors:
Antonio Diaznegrillo
About:
Medical research · Bioinformatics
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