Is there any resource available from which we can extract the list of genes/proteins involved in social immunity of insects?

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Chris G C Jacobs

That depends on the species you are working on. Furthermore, to my knowledge there is no such thing as social immune genes. Lysozyme is secreted and for that reason it is a subject of social immunity. But not in non-social insects. So i guess you are looking for immune genes in general but in social insect. Could you be a bit more specific?

Shishir K Gupta

Hi Chris, I recently read some literatures mentioning the contribution of genes in social immunity in social insects. I am not looking for the immune genes in social insects but the proteins/genes from social insects that can contribute in social immunity.

So the short answer would be, no there is no such list. There is very little known about social immunity especially on the molecular level. It is a combination of antibacterial secretions with behaviour (grooming for example). I would look for immune genes that are secreted as a start. Also look at papers of Nicrophorus (the burying beetle), which is used to study social immunity. Lysozyme is the best studied secretion sofar.

Abid Hussain

Social insects especially termites have different layers of defence that ultimately provide immune resistance to the nest mates. Contrary to other social insects such as honey bee etc little work has been done to explore the molecular mechanism of termite resistance (Immunity) to pathogens. Recently, I have uploaded approximately 4000 EST from immunized colony members. Among them approx 500 identified ESTs were directly or indirectly related to immunity some of them can be download from the link http://getentry.ddbj.nig.ac.jp/getentry/na/KC571836-KC571990/?filetype=html&limit=100

If you want i can send to you the rest.

My further exploration on the proteome analysis and behavioral studies enable me to suggest that Insect pheromone-binding family OS-D might play an important role to bridge the mechanism of immunity and repellency.