Is there any report that cocrystals are less hard than the individual?

10 October 2014 1 5K Report

Pharmacocrystals have lower hardness than the drug. Any report in the literature?

Voriconazole cocrystals with 4-hydroxy benzoic acid, 4-aminobenzoic acid and fumaric acid are less harder even than the pure voriconazole, which is reported to be too soft to make tablet.

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