I used DHEA-S (Dehydroepiandesteron Sulphate) in a study as the biomarker of ageing. DHEA-S is hormone secreted from Supra renal gland, gonads and even adipose tissue. DHEA-S is gradually decreasing when age advances.
In addition to this, what are possible biomarkers to measure the intensity of biological ageing process in humans?
Thank you vry much. I will do reference.
When you define "ageing", you may then go for some... biomarkers. Telomere attrition (with the exception of many cancer cells) can tell about the relative number of cell divisions or, perhaps, some difference between aged cells vs controls (long and short arms are equally important); accumulation of some bulky proteins, agregates etc can give you another indicator. On a physiological levels - just look for an ABC book in gerontology to some tests.
So far, all attempts tofind specific markers for "measuring ageing" failed.
Thank you for your expert suggestions. Really, i am impressed on the fact that some people are in our society, they look young than their chronological age. Contrary, some look more older than their actual age. So what are the factors affect on the process of ageing? And then, how to measure one's rate of ageing? Anyway, I accept your views.
The level of specific sex hormones can be used as a marker but also the length of the chromosome telomeres (and the level of telomerase)
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