When we plot glucose consumption, ethanol production or growth curve in a fermentation process, most of the time we can not get a smooth line connecting the data points. I found some articles e.g.:

1. Alfenore et al. (2002) Appl. Microbiol. Biotechnol. 60:67–72

2. da Cruz et al. (2003) J. Inst. Brew. 109(4): 349–355

These authors seems to use trend line on their graph, since I noticed that the line are not exactly connecting the data points.

Is there anyone know that we may do that? if the answer is yes , can anyone suggest what regression used for those curve and refer me to any reference that mentioned this?

Thank you in advance.

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