Good luck

Hi İrem Bahar Gül

If you are after a mathematical model for liposome formation, there are only a couple of relevant published work:

e.g.;

Torre, L. G., Carneiro, A. L., Rosada, R. S., Silva, C. L., & Santana, M. H. A. (2007). A mathematical model describing the kinetic of cationic liposome production from dried lipid films adsorbed in a multitubular system. Brazilian Journal of Chemical Engineering, 24, 477-486.

However, the physicochemical factors governing formation of bilayer vesicles are described in the following papers:

Danaei, M., M. Dehghankhold, S. Ataei, F. Hasanzadeh Davarani, R. Javanmard, A. Dokhani, S. Khorasani, and M. R. Mozafari. "Impact of particle size and polydispersity index on the clinical applications of lipidic nanocarrier systems." Pharmaceutics 10, no. 2 (2018): 57.

and:

Mohammadabadi, M. R., & Mozafari, M. R. (2018). Enhanced efficacy and bioavailability of thymoquinone using nanoliposomal dosage form. Journal of Drug Delivery Science and Technology, 47, 445-453.

In which you can read:

"The underlying biophysical principles and the mechanism of formation of lipid vesicles, including liposomes and nanoliposomes, are explained by Lasic [81–83], and Mozafari [54,84,85]. In brief, nanoliposomes are formed when their ingredients (mainly lipids and phospholipids) are placed in an aqueous medium, such as dH2O or bu"er, and subsequently form bilayer structures, once adequate amount of energy is supplied. Input of energy (e.g. in the form of agitation, sonication, homogenization, heating, etc.) results in the arrangement of the lipid molecules, in the form of bilayer vesicles, to achieve a thermodynamic equilibrium in the aqueous phase [54,82,84,85]."

Let me know if you need any of the mentioned articles.

Thank you M. R. Mozafari , ı will check it.