I am looking for IRB approved protocol approaches on how to handle Incidental Findings (IFs) in EEG research. Starting from Wolf, et al. (2008). Managing incidental findings in human subjects research: analysis and recommendations. The Journal of law, medicine & ethics, 36(2), 219-248. who mainly refer to fMRI and genetic studies where the problem seems to be clear(er), I try to find prevalence for IFs in basic EEG research and clinical EEG research (e.g., epilepsy research).
Are there any established protocols how to handle IFs in EEG research?
Please let me know if this reference/site may be helpful to you:
Evolution of universal review and disclosure of MRI reports to research ...
https://www.researchgate.net/.../293641319_Evolution_of_universal_review_and_disclo...
Article (PDF Available) in Brain and Behavior 6(3):n/a-n/a · February 2016 with 21 Reads .... 34% of research participants had an incidental finding identified, of which .... EEG). MRI scans from 216 studies by 63 investigators. using three scanners (Siemens 1.5 ..... able costs per scan if the IRB mandated radiology review.
Dennis
Dennis Mazur
For those interested in incidental finding guidance for research reporting, these references/sites may be useful to see the approach of others, but be sure to check with your relevant IRB(S) for what they require.
1. Magnetic resonance imaging of … - Weber - Cited by 208
Prospective study of new-onset seizures presenting as … - Singh - Cited by 65
Unexpected - The Mind Research Network
https://www.mrn.org/files/.../Expect_the_Unexpected_Shoemaker_IF_article_2010.pd...Cached
Aug 2, 2010 - is based on using multi-modal imaging (MRI, MEG, EEG), genetics ... board (IRB) mandated that a neuroradiologist review all readable. MR images. ... identify incidental findings, of which 2 percent to 8 percent are clinically ...
2. Guideline for the Reporting of Incidental and Secondary Findings to ...
https://uwaterloo.ca/research/...research/.../guideline_on_incidental_findings_reportin...Caches
Oct 1, 2014 - Incidental findings are “discoveries made in the course of research but that are .... other procedures such as blood tests, ultrasound, blood pressure, EEG, ECG, heart ...... IRB Primer: Incidental and Secondary Findings.
3. Reporting Results and Incidental Findings to Research Participants
irb.utah.edu/_pdf/Incidental%20Findings%20-%20Botkin.pdfCached
on Human Research Protections. Return of incidental findings to subjects. Return of individual ... IRB's: Limited experience with return of experimental results.Missing: eeg
4. Incidental Findings Guide
https://research.ucr.edu/media/32243/incidental_findings_guide.pdfCached
Sep 27, 2016 - As part of research with human subjects, scientists and clinicians should anticipate ... incidental findings should be defined and described in the IRB ... would be picked up by a medical [MRI, fMRI, EEG, EKG, Blood draw, etc.].
5. For Researchers: Incidental and Secondary Findings
https://bioethicsarchive.georgetown.edu/.../Researcher%20Primer%20Incidental%20Fi...Cached
Management of Incidental and Secondary Findings in the Clinical, Research, and ... preferences; and, if researchers decide to return certain incidental findings, .... thoughtfully deliberated and evaluated by an institutional review board (IRB).Missing: eeg
PLEASE BE SURE TO CHECK WITH YOUR IRB FOR THEIR VIEW ON INCIDENTAL AND SECONDARY FINDINGS AND WHAT THEY REQUIRE FROM THE PRINCIPAL INVESTIGATOR AND/OR STUDY SPONSOR.
Dennis
Dennis Mazur
Thanks Dennis,
this is extremely helpful! Unfortunately, some of the links do not seem to work (e.g., the last link) and I couldn't find anything specific to EEG. Do you have any specific link for IFs in EEG research?
Best,
Klaus
This one should iinclude elements of eeg IFs.
Ethical and practical considerations in managing incidental findings in ...
https://pdfs.semanticscholar.org/7c33/409fae7ed3295619000c67ac7ec4b197bf40.pdf
by J Illes - 2002 - Cited by 93 - Related articles
pation, archiving of incidental findings including false positives, and the adoption of guidelines ... To our knowledge, a systematic analysis of incidental findings in research EEG, .... The language was generated internally and IRB-approved:.
Please see attachment.
Dennis
Dennis Mazur
This is a lecture including eeg IF material:
The EEG in epilepsy - Vanderbilt University Medical Center
www.mc.vanderbilt.edu/.../Lecture%205-%20EEG%20in%20focal%20epilepsies-han...Cached
A. Findings may be seen in the absence of epilepsy .... Scalp EEG characteristics of temporal lobe seizures .... l Misinterpretation of incidental or irrelevant. EEG ...
Dennis
Dennis Mazur
Dear Professor,
Please, be so kind and forgive me for being somewhat late in reply. However, if you happen and glance over my latest research proposal, Entropy Driven Deep Learning, you will find that my area of work is limited to neural net, proactive vision, etc. I am sure you will forgive me for not being able to provide an appropriate direct response. Yet, in this submitted proposal, and few other which will follow shortly, you will certainly find involvement of both Beta and Alpha manifests arising from rapid shifts of attention.
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