If you are using a recent release of ANSYS you have to go in Engineering Data and you have the option to define an orthotropic material (it depends by license). In addition in ANSYS there is ACP that is the module for composites but you need of the apposite license.

If is possible to define your model as shell it's possible define more layer on a single shell (probably also the angle) and it could be a good method, beacause a lot of users make in this way.

Calculate properties material it's very hard in ANSYS, usually is the producer of material that inform the FEM analyst.