Can nanoparticles access the brain after intranasal adminitration by endocytosis?

I found that functionalized nanoparticles (190 nm) can reach the brain easier than transferrin-functionalized nanoparticles (210 nm) after 30 minutes of an intranasal administration. Is it...

09 October 2018 5,719 1 View

Can I freeze at -20 C E coli suspension for posterior extraction of DNA without affect its integrity and purity?

I am using the QIAamp DNA Mini kit 250 from QiaGen for purify genomic DNA from E. coli. I have a biomass and I am looking for the best storage conditions because I am not going to perform the DNA...

06 August 2018 9,171 2 View

Can anyone identify this type of calcite crystal?

This is a SEM image taken after 7 days of carbonation of nanolime at 60-80%RH. Those crystals were found as pure calcite by XRD, which were fully oriented to {104}. Can anyone with experience on...

17 June 2018 2,446 27 View

Significant stored energy has been released means that likelihood of much larger earthquakes in the region has reduced now. " Anyone questions this??

"However, since two major earthquakes of magnitude 7 and above have occurred in a matter of 10 days in the region toward southern part of North American tectonic plate, significant stored energy...

08 September 2017 900 1 View

Any approach to accurately quantify low protein concentrations (10-500 ng/microL)?

27 October 2014 6,599 11 View

Does anyone know of research on business model innovation for mining industry towards sustainability?

I am exploring topics for my master thesis and I am very interested in business model innovation for sustainability applied to the mining sector since in countries such as Colombia, where I come...

01 February 2014 8,184 2 View

What does "MS-revised medium supplemented..." mean?

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12 September 2013 7,972 2 View

What's the poing on installing an AC/DC/AC converter to a SCIG wind turbine?

Besides for protection purposes, if you install the SCIG to the grid through a transformer, the system automatically achieves the balance between the mechanical and electromagnetic torque...

01 January 1970 8,497 6 View

Nice paper from Prof. Bastarrachea's Lab at UTSA: https://www.ncbi.nlm.nih.gov/pubmed/24553120

01 January 1970 913 1 View

Interested in connecting this with our Cellulat system?

01 January 1970 7,948 0 View

What degree of missing data in a particular case/participant results in Expectation-Maximisation no longer working?

I'm dealing with a mediation model and am using the PROCESS module in SPSS. Due to SPSS and PROCESS being limited in the imputation methods - being unable to handle multiple imputation - the other...

02 March 2021 4,362 1 View

How to compare 2 samples recruited with different sampling methods?

If I want to compare characteristics of 2 groups of patients, one group is recruited from a random sample of the general public while another group is from a sample with a fixed gender (male to...

26 February 2021 3,526 3 View

How to interpolate from a time-series database ?

Hi, I am having trouble with a problem, in the field of Optimal Control and the generation of optimal time-series. Let's consider a system, whose dynamics are represented by dx/dt =...

24 February 2021 9,105 2 View

How to run raise regression in R?

if anybody know how to run raise regression in r, and raise parameter selection, please help me

24 February 2021 8,199 1 View

Do you consider undergoing a structure literature review / Meta analysis and getting numerical findings sort of quantitative method?

I am looking for a classification of the research methods included in literature review papers or Meta analysis ones .

22 February 2021 1,131 4 View

Hi all, My research questionnaire has 3 sections each having a mix of yes/no and multiple choice questions. How can I test its reliability ?

The sections are about awareness, practice, and perception regarding waste management. Thanks

20 February 2021 5,722 3 View

Can I do two kinds of mixed method in explanatory research?

Dear distinguish professors and scholars, I have a research in measuring two kinds: think tank capacity and research impact on policy. Can I do two kinds of mixed methods in order to find, "Is...

20 February 2021 6,897 1 View

How to analyse a (perceptual) study using differing/comparable sets of stimuli?

I plan on running an online perceptual experiment that has, let's say, 100 unique video stimuli altogether. Since these are too many to be rated by every participants, I would like to present the...

15 February 2021 7,444 2 View

How to analyse a split-plot design in stata ?

I have run an split-plot design experiment evaluating the efficacy of a treatment (with 3 whole plots and 4 sub-plots), and I am planning to analyse the collected data in Stata. However, I do...

14 February 2021 7,800 7 View

What is the best way to calculate sample size for a multivariate regression model for adequate power?

GPower is only equipped to deal with calculations of bivariate regressions and needs SD s for both predictor samples. However, if one has a multiple regression with more than 2 outcome variables...

12 February 2021 6,911 3 View