Is there a recommended intraperitoneal injection dosage of GPR132 antagonist for Apoe-/- mice?

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Animal model is a diabetic model of Apoe-/- mice (C57BL/6) fed a high-fat diet. Can the GPR132 antagonist 1 (HY-157189) be administered via intraperitoneal injection? What is the recommended dosage?

Lily Watson

GPR132 antagonist 1 is a relatively new small molecule, which is named according to its target. The related literature is limited to a single patent published on our official website. If you plan to conduct animal experiments, the dosage for administration will need to be determined by pre-experiments, typically within the range of 1-10 mg/kg.

The answer to this question is provided by MedChemExpress Technical Support. [email protected]

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