E=mc squared establishes that energy is related to mass in proportion to the speed of light squared. Since that speed is calculated by dividing distance in space by time, it raises the question of whether there are any limits to the spacetime scale in which the equation must hold. If one makes the assumption that energy must equal mass times the speed of light squared on all spacetime scales and follows it to its logical conclusions, it seems to lead to a Theory of Everything that explains the nature of many of the aspects of the universe that physicists don't understand, like dark energy and dark matter for example. I have written a paper that describes this theory.