I'm using Gromacs 5.0.2 for a MD simulation with polymer in a saline solution, but the parameters for the polymers are not know, so I'm using OPLS, but this create a incompatibility with the other components in the simulation.

This is because OPLS is originally developed for a geometric mixing rule for sigma in the LJ 12-6. And the ions and other elements where create with arithmetic rules for sigma. 

So, how to combine or adapt in a MD simulation when you have these situation?

Or if there is a set of parameters for polymers that use an arithmetic mixing rule easy to insert in the Gromacs program?

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