Yes, you can carry out your study with different fuels such as biodiesel. engine performance parameter varies with the different types of fuels.

Thanks Vishnu Kumar

May i know is it forte in anysy or some other workbench?, to carry out study with different fuels.

Yes, use libraries from Ansys Chemkin

thanks Olexiy Shynkarenko

yes, you can use fuels from the fuel directory or add your own composition in licensed version of fluent.

thanks Neeraj KUMAR Yadav

Yes it should be possible with ANSYS, I am sure of that with COMSOL Multiphysics once you have the CHEMKIN format of the fuel in question. This I know should be the same with fluent.

thanks Olumide Adewole Towoju

Yes, but you need variable compression ratio.