I am curious to hear the opinion of the scientific community about the "chick embryo cancer model" or "chick chorioallantoic membrane assay"? How reproducible and reliable is this model? What is the experience with mortality of chick embryo? Is there any tricks to master to infuse anti-cancer agents into chick blood vessels? Any good reliable source of information?

In principle this model can be valuable as an intermediate phase between cell culture tests and mice model as long as it is reproducible and easy to handle.

Your experience will be appreciated.

Thanks!

Thierry

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