Is anyone working on biomarkers to differentiate between bipolar I disorder and schizophrenia?

More Mladen Yordanov Mantarkov's questions See All

Heat transfer coefficient on shell side of shell and tube HE?

Hot water enters on the shell side and cools along the tubes. Why does the heat transfer coefficient decrease along the tubes and have a lower value at the water outlet? And why does the heat...

17 October 2022 3,642 4 View

Where have be found good examples of Performance evalutions criteria (PEC) for Heat exchanger with cicrular finned tubes?

One good literature source is R. L. Webb. Principles of Enhanced Heat Transfer, Taylor & Francis, 2005. If there are more good sources to recommend? What criteria are most applicable in practice?

04 March 2017 6,159 5 View

How to set correct Convergence Tolerance?

I am solving heat finned tube heat exchanger. At Residual monitor is default setings for Convergence Tolerance. All values is set to 0,001 exep energy to 1e-06. If velocity of air at input is 2...

31 January 2017 1,182 9 View

Does Inflating layers need to be on both sides: on fluid and solid body?

Object of interest is fluid flow over tube in heat exchanger. Does Inflating layers need to be on both sides: on fluid side (air) and solid body (tube)? If yes, thus number of layer have to be...

14 January 2017 1,294 5 View

Capillary flow in PHOENICS?

Currently, I am working on the simulation of capillary flow in PHOENICS. The idea is to insert the PATCH with pressure conditions as the result of surface tension. I'm am using H-O-L and SGS as...

08 January 2017 4,166 1 View

Does anyone know of any work where time-out in volleyball is processed?

Does anyone know of any work where time-out in volleyball is processed? Thanks. Time before the calling time-out... time after finished time-out?

27 December 2015 6,528 4 View

Reversibile flow on outlet in ansys Fluent?

I make calculation of my model of finned heat exchangers by Ansys Fluent. Model is somewhat complicated and have abut 5 millions elements and 8 inflation's layers. I chose k-epsilon method for...

01 January 1970 3,867 12 View

How to solve divergence problem?

I am trying to solve my model of heat exchanger with finned tubes in Fluent. First variant with air velocity of 1 m/s converged after cca 550 iteration in k-epsilon model. Now I choose velocity of...

01 January 1970 9,569 17 View

How to import correct model for ANSYS FLUENT?

I made a model of the heat exchanger in SolidWorks. The goal is to make numerical simulation using ANSYS FLUENT (ver 15.0). So far I have not used the said program is likely to be adapted designed...

01 January 1970 1,758 3 View

How to define the air properties in the heat exchanger calculation: as constant or temperature dependent?

I calculate Heat exchanger air-water, the air is heated. The air at the entrance is about 20 C. Ansys offers the ability to define air properties (density, thermal conductivity, dynamic viscosity...

01 January 1970 1,069 2 View

How to label synapses in over-fixed mice brain sections (40 um) via immunohistochemistry (IHC)?

We have mice brains that were over-fixed due to old PFA used during perfusion. Thus, the synapses are no longer being labeled by the Synaptophysin (SY38) mAB. which works perfectly every other...

17 July 2024 7,767 3 View

How can reinforcement learning algorithms be effectively applied to study decision-making processes in neuroscience?

I am interested in exploring the intersection of neuroscience and AI, particularly through reinforcement learning for understanding decision-making in the brain. I also want to integrate...

17 July 2024 1,225 0 View

What is the difference between neuropsychology and cognitive neuroscience ?

The main differences

14 July 2024 3,158 4 View

Does the temporal summation of EPSPs accumulate linearly to action potential threshold or logarithmically to a plateau/limit?

I am attempting to determine which current inputs (in uA) are subthreshold for inducing a burst of activity. This is because I am attempting to model DBS form epilepsy in vitro, which clinically...

23 June 2024 4,083 1 View

Our -20 Freezer thawed unexpectedly, can freeze-thaw of K-glu internal solution cause issues obtaining Gigaohm seals?

We are an electrophysiology lab out of Milwaukee. Recently, due to ice buildup, a small crack in the door of our -20 freezer resulted in all of the freezers contents reaching room temperature...

06 June 2024 2,234 1 View

Internationally recognised publishing outlets specialised in publishing science-based futuristic papers?

Does anyone use or know of any internationally recognised and reliable publishing outlet (i.e. Journals) that are specialised for submission of "futuristic" articles which are based on the...

28 May 2024 2,946 2 View

How can we effectively model RPE signals at the single-trial level in EEG data?How can researchers disentangle overlapping ERP components effectively?

Dear all, I need your expertise on this matter. I have an article under review and I got some comments that I need your help with: In my research, I investigated the FRN (200_300ms post_feedback...

23 May 2024 4,953 0 View

Can anyone explain why my EGFP expression increased (but Ai9 RFP decreased -like normal) after imaging with a confocal microscope?

I have been trying to image a receptor in the brain for weeks now. It is an EGFP-cre G-coupled protein receptor. The model is a iCre based EGFP KI mouse model crossed with an Ai9 reporter line. I...

23 May 2024 7,776 2 View

Can you describe the process for initiating and titrating clozapine therapy in a patient with treatment-resistant schizophrenia?

Optimizing Clozapine Therapy: Overcoming Challenges and Enha... Can you describe the process for initiating and titrating clozapine therapy in a patient with treatment-resistant schizophrenia?

12 May 2024 6,010 2 View

Research about impact of brave and persistence?

I want to read about studies or experiments who proved that being brave and persistent are suceeding factors. Are there any new aspects or findings e.g. from neuroscience?

12 May 2024 4,614 3 View

Hendrika Vande Kemp

Check out the following article at the National Institutes of Health https://www.nimh.nih.gov/news/science-news/2015/biomarkers-outperform-symptoms-in-parsing-psychosis-subgroups.shtml

Mladen Yordanov Mantarkov

Thanks a lot for the suggestion. We were aware of the RDOC project, but I personally never thought of discussing our results in the context. Brilliant!

Peter Prudon

Mladen, you may profit form the discussion on another question:

https://www.researchgate.net/post/Why_are_there_no_negative_symptoms_with_schizoaffective_as_compared_to_schizophrenia/1

Craig Wagner mentions research that does find something and I comment on a study with negative results.