I am checking cytotoxicity of drug molecules by using ascites or tumour tissues. Challenge is reproducible data as primary have passage limitation and cells number too limited for so many experiment at a stretch.
Thanks
1. A bcc metal single crystal was sliced along (1 -1 0) plane for TEM study. Assuming that the TEM available is equipped with a goniometer stage which tilts up to 45o. The Burgers vector of...
20 February 2021 2,370 1 View
I have made neosome from herbal drug. Neosomes are stable. But I face problems in dissolution. I used minimum ratio of 1:1:0.25 ( Drug:span 60: Cholesterol and GMs. Now how can I active better...
17 February 2021 3,584 1 View
We are planning to make Polymeric nanoparticles for co-delivery of 2 flavanoides. Which is the best method, that one should follow.
09 February 2021 7,086 8 View
Hello, Has anybody published with OmniScriptum Publishing Group. I got an email from them. The emails claims the editor is from the group but the email is signed out by lambert academic...
08 February 2021 5,611 3 View
Even after few repetitions..I am getting similar results. Is is due to organic components?
20 January 2021 9,279 6 View
To have the desired grain size in 6061 and 6063 Al alloy, what should be the minimum % of Ti and B pick up and what is the chemistry/metallurgy behind that?
07 January 2021 9,305 2 View
Kindly provide the technical papers/patents on the production of AlV50% alloy by thermit route, by using V2O5
05 January 2021 2,471 3 View
FeAl and Al wire has applications in Steel for deoxidation. I want to know the other application of various grades of FeAl. Does Al wire also has other applications apart from deoxidation? Regards
27 December 2020 8,435 1 View
There is a different behavior in carbon steel and stainless steel. Drastic low recovery in carbon steel due to high melting temp. But in ss , working temp is high so dissolve at 1668 degree temp....
16 December 2020 8,765 8 View
I need Coronary Angiogram Images(CAI) publically available dataset. Coronary Artery Disease (CAD) is a condition of the heart due to atherosclerosis. Atherosclerosis is the narrowing of arteries...
07 December 2020 6,470 3 View
02 March 2021 3,060 3 View
Estemeed colleagues, I found some issues regarding the quantification of the data for TNBS assay. There are different protocols on how to perform that but it is clear to me the "fil rouge" that...
02 March 2021 2,616 1 View
Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...
01 March 2021 3,867 3 View
I am a research scholar working on heavy metal stress on plants. I will be doing biochemical characterisation( protein, carbohydrate, proline, antioxidant enzymes and many more assays) at interval...
01 March 2021 6,999 3 View
We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...
01 March 2021 3,355 3 View
I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...
01 March 2021 3,703 3 View
I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....
01 March 2021 3,607 3 View
Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...
01 March 2021 8,169 2 View
I'm a student and I have to produce a cell line with a knockin for the NRF2 gene with GFP. I have to put a promotor in front of the GFP because the gene will be too far away from the promotor of...
28 February 2021 7,127 2 View
Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?
28 February 2021 1,577 1 View