I think only in acidic media may lead to ring opening of furan ring and it's derivatives . Any way you can check basic effect by monitored with IR spectra.please let me know what is the results.

Thank you very much, Alaa.

Best,

According to the MSDS of THF https://fscimage.fishersci.com/msds/23010.htm , it is incompatible (will react) with caustics (even with NH3, NH4OH, Ca(OH)2). Thus I think, the ring of THF derivatives can also be opened with strong basis.

Dear Imre:

Thank you so much for your answer. It is really useful for me.

I did not find información about stability of 2,5-dimethylfuran into strong basic medium.

Best,

Auréa.