1. The Idea of alternative nucleon states is suggested by the near-identity of the masses of neutron and proton.
2. Charge Independence into one of Charge-Symmetry.
3. A new Quantum number : Charge Parity tells us about the nuclear wave function - Whether is it an even or odd.
http://www.scientificamerican.com/article/elementary-particles/
http://www.nature.com/nature/journal/v172/n4378/abs/172576a0.html