In India Navratri celebration are done for 9 days in which people do fasting (different patterns) , however the effect of fasting on health during Navratri has not been explored , with different studies exploring the same effect on festivals like Ramadan. We carried out a pilot exploratory study among 50 healthy adults willing to perform intermittent fasting (Fasting period of 12 hours) .Anthropometric , Biochemical and inflammatory parameters were assessed before fasting and day after completion of fasting .There was a significant reduction in Body Weight, Waist Circumference and Hip Circumference during the intermittent fasting period . There was significant lower levels of Total Cholesterol and LDL . However, there was a significant increase markers like TNF-alpha, IL-1, IL-6, and IL-8. How can we justify our results showing reduction in key Anthropometric parameters and biochemical parameters like cholesterol in a short span of 9 days and paradoxical increase in pro-inflammatory markers?