I'm looking for the %injection dose of doxorubicin that accumulates in a human tumor. The %injected dose/kg for humans (in clinical trials) would also be extremely helpful!
Thanks! The type of tumor matters less, I'm trying to make a comparison between the tumor accumulation of free chemotherapy vs. nanoparticle-encapsulated chemotherapy.
For some reason, the data for nanoparticles is easy to find, but free drug is very hard!
I just need a range of %ID/kg (ID-injected dose) in humans, for free chemotherapy.
Unfortunatley the clinical trial links didn't have any results (they also inted to give AUC results, not ID/kg)...