In which case would eGFR derived from the plasma creatinine likely give a more accurate measure of GFR than measurement of plasma cystatin C?
thanks Maha Fahdil Mohammed for a nice comments and excellent answer.
Good question Moaed!
Possibly where there is thyroid dysfunction (see refs below).
However, remember, that eGFR is not a measure - merely an estimation, and whether it is derived with pCr or pCysC it is not a great estimator.
51. Fricker M, Wiesli P, Brandle M et al. Impact of thyroid dysfunction on serum cystatin C. Kidney Int 2003; 63: 1944–1947
52. Wiesli P, Schwegler B, Spinas GA et al. Serum cystatin C is sensi- tive to small changes in thyroid function. Clin Chim Acta 2003; 338: 87–90
thanks Maha Fahdil Mohammed for a nice comments and excellent answer.
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