The concentration of biomarkers, such as Alpha-Fetoprotein (AFP), has been subjected to ongoing race-based adjustments for BIPOC (Black, Indigenous, and People of Color) populations, with a significant reduction in the percentage concentration over the past few years. However, other racial groups have not undergone similar adjustments, and the information provided in textbooks may not reflect these changes. This raises questions about why biomarkers like AFP are based on race rather than socioeconomic determinants and health. While race may be considered a risk factor, it has been a decade since the last adjustment, highlighting the need for updated and evidence-based approaches.
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