Some persons with epilepsy can self-predict seizures. In these individuals, the odds of a seizure following a positive prediction are quite high and are not attributable to remembering the seizure and are more associated to self-awareness.
Despite the design of new anti-epileptic drugs, drug resistant epilepsy still lacks an ultimate solution . Resective surgery, where the part of the brain that causes the seizures is removed , can only be applied to a small fraction of drug-resistant patients, the outcome of which is highly unpredictable. Additionally, the cause of drug-resistance is unknown. Resistance to the traditional AEDs in addition to the lack of effective seizure management treatments for this large population of patients demands newer, more effective seizure control therapies.