Furthermore, if there is a signal that the virus obtains, would it be possible to synthetically mimic this signal thus make the virus release the DNA randomly, hence making it unable to attach to a host in order to replicate?
I am still very new to this concept. I know that not every Virus uses transduction to invade a host cell, but I wonder if there is a way to target this specific characteristic of certain viruses and make it their weakness.
For basic context to the question I might add that it is clear to me that Viruses bind to specific receptors on the host cell and just transfer genetic information via endocytosis. My question is aimed to understand what triggers the release of genetic information if they themselves can't actually interact or react to their surroundings.
The only rational conclusion I have been able to acquire by thought alone, was that the host cell itself initiates the interaction and almost sucks it out of the capsid. But as much I would like to believe this, I find it a quite unsatisfactory conclusion as I myself can't rationally explain the steps of this hypothesis.
I would greatly appreciate any assistance.
I'll try.
Virions are the virus turned to stone, this means that do not react to anything. The virus is when it is transfered to the host. The fact of transmiting the genetic material to the host is due to molecular recognition. If this is not there it won't do it. You may say the virus "lies", the virus tells the lymphocyte what to do,but if this molecular recognition does not exist it does not inject its genetic material. Maybe say it is a general recognition molecule or maybe more specific. HIV(AIDS) is causing this trouble because it attacks the Th4 cells. The help of the help.
The virions sense the environment and is why the virions turns to virus. This means it infects and inserts its genetic material. You may then say I show virulence or you hide for years and the only thing I do is show up when for example the inmune system does not attack. Less than virions are viroids, transposons or random jumping material. I do know the material does not always get inserted onto the cell. Sometimes they cammuflage and nobody reliases it. (if it is not on the host is it like electroporation, the DNA floating , or I bring the DNA around?). The virions sense the opportunities and they come and infect. We use virus for vaccines and for BAC libraries (YAC is yeast). We do encapsulate the genetic material as a tool in a protein. We make sure it is the right size for it. Some virus are morenused than others. Lie to the virus? Can we make it see the molecular reco-ntion is somewhere else. (I am more worried about the compartments). Sometimes the cell takes it and sometimes its the virus. Sometimes the virus fights
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