Obesity being a major problem for our Diabetes patients, GLP1A therapy has become a boon for them but on routine examination if a Thyroid scan shows either a single nodule or multiple nodules, is it safe to start GLP1A for them?
Fazleh Mahomed
Thanks for this question.
There is an association between GLP1 agonists and medullary thyroid cancer.
But the other types of thyroid cancer also express GLP1 receptors.
https://www.mdmag.com/medical-news/glp-1-receptor-agonists-and-thyroid-cancer-differentiating-cancer-type
It is wise to avoid GLP1 agonists in a case like this, until we have more robust data.
You will actively try to exclude thyroid cancer in this case anyway. [ suspicious clinical features/ultrasound features/ FNA if nodules >1cm]
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