Ideal Sample size to perform mRNA expression studies on clinical samples (Diabetic Neuropathy)?

04 April 2013 1 6K Report

I have initiated the study with 3 cases and 3 controls for gene expression among Peripheral diabetic neuropathy subjects.

Christer Zøylner Swan

Dr. Ayyappa,

this sounds like a very small number. You´ll have to perform a strength/power assessment/calculation. Based on data from similar studies you should be able to calculate the needed sample size to avoiding a type 2 error.

I wish you the best of luck!

Regards,

Christer Swan Andreassen

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