Hello Haroon,

The ideal polymer depend on the final target application, e.g. a dental injectable gel for regeenration e.g. bone, collagen, or drug release, or etc. what would be other components Neverthless, there are number of general parameters including the biocompatiblity of the polymer, rheology of gel, solubility/melting properties of the polymer, the possible reaction between polymer and other component of the gel, gelling time, the maximum force require for injection with different needles, etc. Please be specific about your target application and other compositions in the target gel matrix.

I hope it will help

Amin

I agree with Amin, but above all this you need to be sure the gel is sterile and biocompatible and there is strong clinical support for the application.

This question needs to be more specific firstly,the choice of polymer system involved is performance oriented.

Dear Haroon Rashid , there are few ideal properties should posses the polymeric material for the formulation of injectable hydrogel system those are following:

1. The reaction temperature should not change during the reaction after injection in to the body (during gelation)

2. Polymeric material viscosity should be lower than 50 cp

3. Polymeric material should not exert any osmotic pressure over the surrounding tissue or cells.

4. injectable polymeric solution gelation time should not be very fast or not very late its lies between 2-5 min in range ideally.

5. the hydrogel system should should not leave any by products during gelation reaction.

6. hydrogel should posses High gel fraction and very low sol fraction valuse.

7. polymer for hydrogel should completely dissolve in water

8. Hydrogel and their pre-polymeric solution should be hemocompatible and biocompatible and degradable.

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