Cadmium has 8 stable isotopes with mass:charge (also written m/z) of 106, 108, 110, 111, 112, 113, 114, and 116. Which m/z did you measure in your analyses? Other elements with these m/z include 106Pd, 108Pd, 112Sn, 114Sn, 116Sn.

Sometimes elements recombine in the plasma to form transient polyatomic molecules such as 39K2160 (m/z 110), 95Mo16O (m/z 111) etc ... (the first page of May and Wiedmeyer 1998: https://www.perkinelmer.com/CMSResources/Images/44-74379ATL_TableOfPolyatomicInterferences.pdf has a number of other polyatomics relevant to Cd).

Essentially, the reviewer is asking you to consider if there is another element or polyatomic that might be causing the Cd signal your ICPMS observed.

Thankyou Matthew Wheal for your answer, actually i dnt have a chemistry background and i belong to biological background, moreover we had the sent the samples to a organization for ICP-MS. What do you think would be the answer or what should i ask from the organization that performed the test. Thankyou.

Ask the laboratory that ran your samples for a list of the isotopes they monitored. Explain why you want to know and I'm sure they will be able to help you out. You want enough information to demonstrate there were no oxides formed in the plasma or either tin (Sn) or palladium (Pd) that was masquerading as Cd.

Thank you Matthew Wheal , very helpful answers. appreciated

Agree with Matthew Wheal on his recommendation to seek answers from the lab who performed the analysis. If the party, who did the analysis is regularly performing elemental profiling they will sure have internal standardized methods to reduce noise and matrix interference.

Another this to consider would be whether there was any use of QC materials (either internal standards or external quality control materials such as (Certified reference materials)). If the analysis can hit the levels of the standards that will also help make your case.