The first two respondents have said it clearly. Though not new, drug resistance in TB is still existing. The new thing now might be the effect of COVID-19 regarding access to drugs, diagnostics among others. I highly recommend you join a research group in that line of research. you will get more information about what is currently happening in that field
I think your research topic on M. Tuberculosis depends on your research interest but currently the impact of COVID-19 on the incidence of tuberculosis will be a good area to look into.