on which so for no work is done please help me finding proteins which 3D structure and drug is not discover yet
Jpred only does secondary structure prediction not 3D.
The PDB and CHEMBL could be a good places to start your search:
https://www.ebi.ac.uk/pdbe/
https://www.ebi.ac.uk/chembl/
As I understand you are first looking for a "diseased" protein to work upon and later it's structure prediction. So, this protein should have an implication directly in the progression of disease due to mutation (like in human cancer) or a pathogenic protein? Anyway searching in the PDB is a good start, you can read about them and their function. But that means the structure is already present in the database.
You have to search for a protein whose structure is yet not elucidated? I would suggest to do a little literature search. Find one human disease on which you would like to work to narrow down your search
Chetna Tyagi thanks for your suggestion i try the same procedure and find a protein involve in cancer and many other diseases its PDB structure is also not predicted
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