How can I use Permanova to analyze individual variation with RNA seq transcripts and multiway Anova design?

I have a dataset with 96 individuals and 1496 transcripts of interest. I have analyzed the experiment by multiway ANOVA in the Permanova platform of Primer-E. I am satisfied that I have figured...

13 February 2021 7,217 4 View

Does anyone know of an anti-rat CLEC-2 antibody for IHC?

I am looking for an anti-rat CLEC-2 antibody for IHC in rat lungs. Has anyone come across one? There are a few mouse ones but the data sheets don't say they cross react with rat, and the ones that...

06 December 2020 3,511 0 View

Help finding right expression to fit data?

Hello, I have some data that looks like the line on the right, but I'm not sure what function to use. It seems like an exponential added to a line, or something of the like. I think it may be the...

18 November 2020 2,357 3 View

Single-turnover kinetics question?

It is my understanding that single-turnover reactions isolate the chemical step, as opposed to being comprised of the chemical step + product dissociation as in kcat. Here's my issue though....

13 November 2020 2,494 7 View

Contrasting singular means?

Does anyone know of a method or approach in SPSS to contrast singular mean scores of overall samples, based only on the overall mean value, standard deviation figure and sample size? The data is...

29 September 2020 5,872 6 View

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09 July 2020 9,914 1 View

What are some good recommendations for free software that could be used to quantify video data on juvenile fish behavior and swimming activity?

Ideally I would like to use free software that can be used with a Macintosh. My objective is to quantify individual swimming patterns from 2-dimensional video data. I would like to collect...

16 March 2020 7,635 3 View

How to compare drug plasma concentration with drug-target binding affinity?

I have two types of data, one is 200 drugs' plasma concentrations, another is the binding affinity(Ki, Kd or IC50) between drug and its targets downloaded in Chembl database. Now I want...

10 March 2020 2,174 3 View

Can anyone recommend a journal focused on "assessment & evaluation" in education that looks favourably on qualitative research?

Looking for a place to submit an article related to assessment and evaluation in physical education that was rejected clearly due to being qualitative in nature.

06 February 2020 3,229 2 View

Do database on materials (i.e. wood, polymers including all type, cement, etc) vulnerability toward weathering exist?

Dear all, Is there a database that provides the vulnerability/degradability information of different matrix toward weathering (i.e. the matrix of product used for outdoor application: paint,...

06 November 2019 8,340 1 View

What could be the reason for not having further low chi square value (better agreement) in my refinement result?

I have tried every combination of parameter changes and after that i have a poor chi square value. I can't get it lower any further. I know there have been a lot of discussion about Rietveld...

26 February 2021 8,480 3 View

Why CHi^2 is reducing if I divide the intensity by a constant factor?

I was refining my XRD data in FullProf. Highest intensity was 400000. The fitting was good but still the Chi^2 value is very high (0.174E+04) I divided the intensity by some constant factor (say...

17 February 2021 3,383 5 View

What is the relationship that determines the depth of the mechanical cultivator with the age or size of the weed For crops planted in lines?

the great depth of the cultivator may lead to passage under the roots without killing them and may give negative results to break up the soil below the roots, increasing their activity, especially...

03 February 2021 3,198 7 View

How do I refine a specific region of my protein model so that it perfectly superposes with a template peptide PDB with the same sequence?

I have a protein model and want to replace a 12-amino acids-long region within the center of the model with those of a PDB file containing a 12-amino acids long peptide of the same sequence. This...

02 February 2021 779 2 View

Does the subsoil have an effect on the spread of weeds whose roots are more than 35 cm deep?

For weeds whose roots deepen more than the level of subsoil, they may be affected by this layer, for example, determined by height and growth, as well as limited to flower production and seeds.

01 February 2021 1,940 4 View

Is it possible to do Reitveld Refinement on single crystal XRD data?

I tried to do single-crystal Rietveld Refinement on my single-crystal XRD data using the option "refinement on single-crystal data/ integrated intensity data" in Fullprof but it is giving error...

30 January 2021 7,813 3 View

How much Ti and B (in ppm) is required for effective grain refinement and why?

To have the desired grain size in 6061 and 6063 Al alloy, what should be the minimum % of Ti and B pick up and what is the chemistry/metallurgy behind that?

07 January 2021 9,305 2 View

How to write a PHD proposal for a predefined research?

Hello everyone, I am aiming to write a PHD proposal of 1000 words. The research is described by the supervisor. That means, research questions, aim, and instruments are well defined by the...

01 January 2021 6,291 7 View

Is it possible to separate the momilactone molecule by GPC device?

The momilactone molecule is present in rice and has an allochemical effect on weeds.

01 January 2021 3,367 3 View

Rietveld refinement. Refined cell parameters are wrong?

I am trying to refine my XRD data with Fullprof software. Although I got low values for R Bragg and Chi 2 factors, when I insert new cell parameters as phase, they don't fit all peaks. In fact,...

18 December 2020 9,322 7 View