I want to use a commercial available material( implant) with some modification and compare it with the original materiel in term of body response and and healing ....
I wrote 10 rats but I could not convince the IACUC to get their approval in behalf of the size of the sample .
*How many rats I have to use in a group, statistically support your opinion?
Dear Mhammed
How are you brother?
You should put 5 rats in each experimental group.
Mazaher
Dear Dr.Mazaher, Mazaher Gholipourmalekabadi
Thank you for replying. And I am doing fine. Hope you are the same.
I should prove validity the number statistically !
It is Ms degree theses.
Happy to hear that you are doing well. I think it depends on the statistics you are using. In the following paper, we used 5 rats for each time interval of each group. Comparisons were made by independent sample t-tests, one-way ANOVA, followed by Tukey’s post hoc test, where appropriate.
Article Fabrication and In vivo evaluation of an osteoblast-conditio...
Mazaher Gholipourmalekabadi
Dear Droc.
what kind of sitting did you use in your experiment?
is it two or one tail experiment ?
like this the following :
Test Family: "t-tests" Statistical test: "Means: Difference two independent means (two groups)."
Under "Input parameters"
Tail(s): "Two"
Effect size d = This is the most important variable. play around the values. The higher the value, the lower the sample size. (Usually, you would have an idea of this from literature)
@ err prob: "0.05"
Power (1 - B err prob): "0.95" some people use "0.80"
Allocation Ratio N2/N1 = 1
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