It is known that many pathogenic/parasitic microbes increase resistance to biocides if penetrate host cell. What would happen with Phytophthora infestans?
Is that true? - I heard of the opposite effect, that biocides increase resistance of the plant against parasites. - Is in general a growing organism more sensitive against toxins?
sensitivity to biocides in plants vs. in vitro
In vitro(the conditions tight) the fungus sensitivity is high towards the biocides, but the sensitivity on the plant in nature is reduced to other environmental factors such as UV radiation, temperature and humidity affecting the biocide, plant and pathogen
In vitro conditions, the sensivity of p.infestans towars the biocides might be high, what I mean by that is the fungi will be more sensitive to the biocide, because all conditions are constant
But in situ, the sensivity might be different ( higher or lower) , why ? because Of the environmental conditions ( rain, temperature, time of applying the biocide...)
@Narimene Mati, I mind biocide degradation by plant enzymes and utilization of plant-provided compounds as factors that can make Phytophthora less sensitive. But, so far I could not find any publication on this matter.
It is known fact for animal pathogens - bacteria inside host cell can be 100 folds more resistant to antibiotics.
Do you consider on specific mechanism for all bacteria? Somethin like a "systemic acquired resistance response" under biotic (plant) stress, which renders the organism also more resistant against abitic stress? - It is many decades ago, that I thought about antibiotics, I was impressed that by the a protocoll in Maniatis, that plasmid-content could be raised by ? chloramphenicol. Oviously many transport systems are regulate by the plant. And, also decades ago, I read about "apoptosis"-like reactions in bacteria (which should be the case as evolutionist consider death an invention of eukaryotics). I dont know about Phythophtora, are there such ancient pcd-systems working. Bacteria in animals might be protected by specific biofilms. - A very interesting topic! Deserves far more research.
@Martin, I am afraid that mechanisms for such phenomena can be quite different for bacteria and oomycetes. Many biochemical mechanisms inside one bacteria cannot work simultaneously, but presence of species / biofilm formation can provide such opportunity (complete cycle of xenobiotic degradation for an instance) and make the bacteria (finally) capable to survive at lethal concentrations of biocides. But, I do not know about Phytophthora...
Pretreat Phythophtora with low concentrations of salicylic acid (and stuff like that, JA maybe) and see if the strains alter their competence against ("other") biocides. - Such a mechanism should anyway exist ("feedback"). I would rather choose Peronospora, but its an interesting experiment.
Well, culturing biotrophs is tricky, as far as I know. - Fred Ausubel works both on plant and animal pathogens. He might know, if there is rudimentary an ancient immune systems in common between oomycetes and plants. - Exciting question - should be
Exactly not similar resistance in vitro and invivo but we get an idea from in vitro study that nearby resistance may be there in vivo. Sometimes, same resistance observed both invitro and in vivo. Kindly refers fungicide resistance in plant pathogens.
- Badges
- Science topic
- Similar topics
- Biological Science
- Microbiology
- Microorganisms