Hi Marcela.

My experience is with prostate cancer xenografts in NSG mice (we find these much better for xenos and PDXs) and they generally run for between 6 weeks and 4 months depending on how aggressive the cell line. I don't know CAL51 but I understand that our breast cancer colleagues run fairly similar length experiments for MCF7 cells. Also, we would never grow to 1000mm3 as that would be much too big for most UK project licenses. We usually go for 100mm3 (so about 4x4x5mm)

Alastair