In liquisolid technology, carrier and coating material in ratio taken the add non volatile solvent then check angle of slide then how weight of carrier and coating material calculated to add in formulation . L f = W / Q
then W = Dose * 100/ drug solubility
so many confusion in calculations in formulation table
plz clear if possible as i have to work on liquisolid technology
Dear Dr. Shaveta Sharma ,
I suggest you to have a look at the following papers where the same method you presented is used:
-Use of the liquisolid compact technique for improvement of the dissolution rate of valsartan
Chella Naveen, Nalini Shastri, Rama RaoTadikonda
Acta Pharmaceutica Sinica B, Volume 2, Issue 5, Pages 502-508 (2012)
Available at: https://www.sciencedirect.com/science/article/pii/S2211383512001165
-Formulation and Evaluation of Liquisolid Tablets of Nifedipine
Arun Raj. R , Ahammed shafeeque A. K and Jyoti Harindran
RGUHS J Pharm Sci, Vol 3, Issue 4 (2013)
Available at: https://www.researchgate.net/publication/322398845_Formulation_and_Evaluation_of_Liquisolid_Tablets_of_Nifedipine
-Formulation and optimization of liquisolid compact for enhancing dissolution properties of efavirenz by using DoE approach
Bhola Jaydip, Mori Dhaval, M.M. Soniwala, and Jayant Chavda
Saudi Pharm J., 28(6): 737–745 (2020)
Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292870/
Good work and best regards, Pierluigi Traverso.
Dear Dr. Shaveta Sharma ,
I suggest you to have a look at the following papers where the same method you presented is used:
-Use of the liquisolid compact technique for improvement of the dissolution rate of valsartan
Chella Naveen, Nalini Shastri, Rama RaoTadikonda
Acta Pharmaceutica Sinica B, Volume 2, Issue 5, Pages 502-508 (2012)
Available at: https://www.sciencedirect.com/science/article/pii/S2211383512001165
-Formulation and Evaluation of Liquisolid Tablets of Nifedipine
Arun Raj. R , Ahammed shafeeque A. K and Jyoti Harindran
RGUHS J Pharm Sci, Vol 3, Issue 4 (2013)
Available at: https://www.researchgate.net/publication/322398845_Formulation_and_Evaluation_of_Liquisolid_Tablets_of_Nifedipine
-Formulation and optimization of liquisolid compact for enhancing dissolution properties of efavirenz by using DoE approach
Bhola Jaydip, Mori Dhaval, M.M. Soniwala, and Jayant Chavda
Saudi Pharm J., 28(6): 737–745 (2020)
Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292870/
Good work and best regards, Pierluigi Traverso.
Dear Shaveta Sharma,
try to follow the indications of the scientific articles I sent you; if you can't understand the method well, try asking someone you know to help you overcome the points that are obscure to you. I have not been able to find simpler informations.
Good luck and my best regards, Pierluigi Traverso.
ok can u give some contacts to whom i discuss my problems related to Liquisolid technology calculations
- Badges
- Science topic