How water-soluble is Losartan?

2 weeks ago 1 6K Report

What is the solubility of Losartan (HY-17512) in DPBS or water?

Hi，

Losartan (HY-17512) is poorly water-soluble and essentially insoluble in aqueous solutions, resulting in precipitation. Aqueous dissolution is not recommended. DMSO is recommended for dissolution.

Losartan potassium, HY-17512A, an equivalent sodium salt, is biologically equivalent to HY-17512. This sodium salt is highly water-soluble. A stock solution can be prepared in pure water and stored in aliquots. Upon use, dilute with culture medium or PBS for immediate dilution.

The answer to this question is provided by MedChemExpress Technical Support.

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