How to test the effect (in-vitro) of mucous on the uptake and motility of nanocarriers, especially in the case of intra-nasal delivery to the brain?

Hemant Motiram Vishwasrao @Hemant_Vishwasrao

02 February 2013 1 5K Report

Mucous will certainly hinder the uptake of the particles intranasally. How do we test the efficacy of our nanoparticles in such conditions?

Sumeet Sood

Please check this article:

Bioadhesive chitosan nanoparticles: Preparation and characterization

Carbohydrate Polymers, Volume 81, Issue 2, 11 June 2010, Pages 243-251

Anitha R. Dudhani, Shantha L. Kosaraju

Badges
Science topic

More Hemant Motiram Vishwasrao's questions See All

Are there any special precautions or reaction conditions during the polymerization of a poly amino acid block copolymer with BOC-NH-PEG-amine?

I am trying to prepare a poly (glutamic acid)-PEG block copolymer from Glutamic acid NCA and using BOC-NH-PEG-Amine. However my reaction is failing time and again.

09 October 2014 7,295 6 View

How does one interpret a result which shows reduced cytosolic expression of a protein but no change in its mRNA levels?

What does it mean if a specific treatment strategy reduces the cytosolic expressions of certain proteins but does not alter the expression of the same protein at the mRNA level? Does it mean that...

07 August 2013 800 8 View

Can anyone suggest a good method for doxorubicin estimation by HPLC (fluorescence detector)?

I am specifically interested in recommendations related to the column and mobile phase. I have tried C18 column but my peak resolution is terrible at pH 4.

05 June 2013 2,292 4 View

What is the most Operating System (OS) which can be INSTALL on Tiny hard devices like Raspberry Pi (RPi) hardware ?

I'm targeting to deploy a mesh network and manually configure MANET routing protocols. I'm preparing scenarios, architectures, and hard devices needed to do that. Are there some step-by-step...

03 March 2021 1,931 5 View

Can we classify HV and LV lines based on line length?

I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...

03 March 2021 4,116 4 View

Anyone plz suggest relevant topic for research in image processing+Deep learning.?

I have selected brain tumor images ...but now found that already lots of research done n this topic.

03 March 2021 5,774 3 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...

03 March 2021 1,401 3 View

Is there a classification scheme for rock cavities or caverns with respect to their size and shape?

The range of forms and sizes of cavities in rock is very big. Is there a classification scheme for rock cavities regarding their size and shape?

02 March 2021 4,511 3 View

Is there a powerful system for the security of the systems distributed on IoT systems?

02 March 2021 3,858 10 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

Which is suitable for use with Python? MySQL or SQL Server?

Which is suitable for use with Python? MySQL or SQL Server? What is your suggestion?

01 March 2021 3,422 3 View

What kind of food stuff increase the potentiality of human brain?

There are different kinds of food stuffs which we intake daily according to our requirements. Carbohydrate, protein, fat, mineral, vitamin, water are mainly working for the growth and development...

01 March 2021 831 2 View

How to Eliminate cosine error and abbe error in LASER measurement system(for example Rhenishaw XL80)?

I like to do project in laser measurement system. My objective is to eliminate or reduce the cosine error, abbe error in Laser measurement system. I have Rhenishaw XL80 system. Please tell the...

28 February 2021 4,890 3 View