I’m implementing a relatively highly cited academic research paper: “Interobserver

Reproducibility of Quantitative Cartilage Measurements: Comparison of B-Spline

Snakes and Manual Segmentation”. In short, the paper outlines how you can get a

B-spline to outline knee cartilage in a 2D slice of an MRI. I am stuck at minimizing the

cost function using gradient descent. I do not know how to gracefully apply a partial derivative to a line integral where the line is a B-spline contour in a 2D image. A full explanation of the problem and my current solution is attached, however I make a poor assumption to get to that solution. If anyone could double check my math or has any ideas I would greatly appreciate it.

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