Oxidation ,hydrolysis and cyclization are the major process problems with enalapril maleate.
TRY IT IN NITROGEN ATMOSPHERE
Hi! Amit,
I would suggest you to use the following excipients and go for direct compression method under control relative humidity.
Lactose
Starch
Pregelatinised Starch
Sodium Bicarbonate
Magnesium Stearate
Aerosil
I have used the same excipients and my formulation is stable.
Regards,
Abhishek
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do the ans
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