In the article "The primary disadvantage of using ATPS to isolate EVs is the presence of dextran in the final suspension of EVs. Dextran interferes with common analytical techniques such as Western Blotting or RNA isolation, affects the viability of cells in vitro and increases the viscosity of the samples, which results in a more heterogeneous distribution of EVs." how can i overcome this problem? Article suggests "Washing steps of the ATPS-EV isolation method is capable of removing phytochemicals and other contaminants from the final isolate of EVs which may interfere with certain assays and studies." addition to the washing steps what can I do to eliminate dextran?