is there any other methods possible to induce psoriasis in rats other than the exposure of the rat's skin to UV radiation?
This article may be helpful for you: Preclinical models of psoriasis. Danilenko DM.
Vet Pathol. 2008 Jul;45(4):563-75
Rat ultraviolet ray B photodermatitis: an experimental model of psoriasis vulgaris.
http://www.ncbi.nlm.nih.gov/pubmed/7734340
If you would be open for mice there is the human xenograft model whereby human psoriatic skin is transplanted onto immunodeficient mice. see eg dephartox.com for a basic protocol description.
I would like to run an efficay study in psoriatic model.
which species is the best; rat or mice?
Our drug work through inhibition of dendritic cell and efficacy has been shown in the K14-VEGF mice model which is very expensive and long
- Badges
- Science topic
- Similar topics
- Biological Science
- Anatomy
- Tissue