Hello,

I'm starting my project, in which I need to use QSAR to search for possible CB2 agonists. To do this, the first step is to create a database containing molecules with known CB2 agonist activity.

I started building my database from CHEMBL, but it provides me with the molecule's activity in Ki or EC50.

So, my question is, how could I differentiate agonists from antagonists in this situation? Is it possible?

Thank you very much for your help c: