Which technique or analytical method should be used to determine the nature of PEG (polyethylene glycol). How do we determine whether it is having branched monomers or linear monomers?
To determine whether PEG has a linear or branched structure, there are several ways to do so. Here are some information from the search results:
-Branched PEGs can be star-shaped, consisting of several linear chains connected to a central core
- PEGs can be synthesized in linear, branched, Y-shaped, or multi-arm geometries
- The steric hindrance of the branched polymer has a relevant role in determining the biological properties of the conjugates
- A branched macromolecule forms a more compact coil than a linear polymer with the same molecular weight, and the flow properties of the two types can differ
I have purchased a custom synthesized PEG. So I need to know the nature of the same, whether branched chain or linear chain. In order to determine that is there any techniques or analytical method?