Dear Arif, you can determine via NMR. Please see this article: https://doi.org/10.1002/anie.200802651

Nuclear Magnetic Resonance (NMR)

Determining the pH stability of an organic compound involves evaluating how the compound's properties, such as solubility, structure, or reactivity, change with variations in pH.

You can use techniques like Nuclear Magnetic Resonance (NMR) or spectroscopy to monitor the stability of the compound under different pH conditions. Changes in spectra can indicate structural alterations or chemical transformations.

It's important to note that the pH stability of an organic compound can be influenced by various factors, including the nature of functional groups, overall chemical structure, and environmental conditions. Additionally, consider the intended application of the compound, as pH stability requirements may vary for different purposes such as pharmaceuticals, cosmetics, or industrial processes.

I hope you find this helpful;

Best Regards!

Thank you