What is the analytical method and instrument required to detect the drug which formed inclusion complex with beta cyclodextrin? How can it be detected?
There are many analytical techniques to determine the CD-drug complex qualitatively and quantitatively for example
UV-spectroscopy and HPLC to detect dissolution constant and for loading and release study
Infra red technique (IR)
DSC ,SEM techniques
You will see different techniques in leatreature review..
I have three outputs, each with a different unit. I am searching for an error estimator with the help of which I can select the most suitable Neural Network configuration. I will have to compute...
26 January 2021 254 5 View
I have a dataset with 19 training points and 6 testing points. At first I defined the rules for 19 training sets and then tried making predictions for the rest of 6 points. But I got all constant...
06 January 2021 3,772 5 View
I am working on developing a predictive drive cycle for a specific city. I have gathered driving characteristics parameters for my target city. I have obtained similar data from previous research...
21 October 2020 6,663 8 View
I can use two/three electrode set up for liquid junction quantum dot sensitized solar cell.
15 August 2020 1,721 1 View
Respected Scientists and Researchers, I am completely new to the field of computational chemistry. I am trying to run GAMESS by taking help of some tutorial videos available on internet. However...
11 June 2020 5,094 1 View
I am sorry if this is a simple question. I am trying to conduct a GWR for hedonic analysis of hotel room rates. For OLS I have conducted analysis including different room types (e.g. double,...
16 April 2020 7,062 3 View
I am trying to implement a model predictive controller to control my soft robot. Right now, the robot is being controlled in an open loop. I have written python code for the MPC but the codes are...
05 March 2020 835 3 View
Why is only femto second laser used. How is it related to terahertz generation?
08 November 2019 6,360 2 View
Consider a simple problem such as cat-classification.. what are some parameters on which an upper bound on accuracy would be expected to depend? Empirical human accuracy is of course a good metric...
08 September 2019 8,019 6 View
I used Autodock VINA for docking.
17 June 2019 9,755 10 View
I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...
02 March 2021 8,437 2 View
We have always used the 96 welled plate, the 48 welled plate but apparently there is much evidence on the 24 welled plate and above all its benefits.It states it is the same you would use on ELISA...
28 February 2021 1,149 1 View
If I want to compare characteristics of 2 groups of patients, one group is recruited from a random sample of the general public while another group is from a sample with a fixed gender (male to...
26 February 2021 3,526 3 View
As random sampling means that everyone in the population have an equal chance to be chosen, can it have inclusion criteria? My research participants have been chosen based on the inclusion...
26 February 2021 6,905 10 View
Hi all I am working on colon-targeted drug delivery for which I kept mice fasting for 6h using fasting grills during scotophase (dark period). I observed liquid fecal content in the cecum and...
23 February 2021 7,701 2 View
Hello, I am running a sandwich-type ELISA where I am trying to inhibit a protein-protein interaction using small molecules. For each experiment, I determine my Z' (Z-prime) to determine the...
23 February 2021 7,429 1 View
Hello, I have run into an issue that has sparkled a debate at work: is the LLOQ/ULOQ impacted by injection volume under the following circumstances: 1) Same dilution factor of all samples 2)...
23 February 2021 9,159 3 View
Hello, I fit a classical dose response curve Y=Bottom + (Top-Bottom)/(1+10^((LogEC-X)*HillSlope)) to my data (not related to inhibitors etc). The model I use is purely qualitative but it fits...
23 February 2021 8,155 5 View
Most developing countries are not ready for e-Commerce? What dimensions and indicators are there to measure e-commerce readiness of a nation? Please share framework or model and evaluation...
22 February 2021 8,132 6 View
I am looking for a classification of the research methods included in literature review papers or Meta analysis ones .
22 February 2021 1,131 4 View