How to compare the binding pockets of two different proteins by overlapping ?

10 June 2024 1 3K Report

I want to compare the binding sites of two different proteins to which the same ligand binds. Alignment using residues in the binding pocket was attempted but was not effective. Are there any tools or methods you recommend?

Farzin Sohraby

Try ProBis

http://probis.cmm.ki.si/

You can find pockets on the protein and I think you may be able to compare them as well.

Best,

Farzin

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