I have a genetically modified mouse line that is showing a characteristic phenotype including low glycolysis levels of the T cells as shown by the glycolytic stress test. I want to test a hypothesis that by boosting the glycolytic pathway the phenotype would change. I tried Metformin and Terazosin with no success. Do you have a suggestion with glycolytic boosting drugs or chemicals, I could use?
I want to boost glycolysis in-vivo and ex-vivo.